This project belongs to the field of modern agricultural technology. The purpose of the project implementation is to develop water-based pesticide formulations. Our country is the world's largest pesticide producer. Millions of tons of aromatic solvents in pesticide emulsifiable concentrates are sprayed into farmland every year, causing serious harm to the environment. Therefore, the promotion of water-based pesticide formulations has received great attention from all over the world. However, water-based pesticide formulations have two major shortcomings: first, the formulation is unstable, and second, the use effect is poor. In order to solve these two bottleneck problems, we systematically studied the surface chemical laws of pesticides and additives, used computer simulation technology to conduct a computation-experiment-computation-experiment cyclic research, and completed laboratory trials of new additives and new dosage forms., pilot trials and industrialization technology promotion have achieved good economic and social benefits. It has greatly promoted the promotion and application of environmentally friendly pesticide formulations in my country. Main technical innovations: (1) Established a new assistant and dosage form design software: Compiled the surfactant data reported in the world literature for more than 50 years, selected the Hancsh equation, established a QSPR mathematical model, and made visual intelligent software. The software can retrieve the structures, parameters and application formulas of existing additives; predict new surfactant parameters, and guide the design of new functional additive structures and pesticide application formulations. (2) Apply newly synthesized additives and software computing technology to develop more than 60 new WDG and SC waterborne pesticide formulations. (3) Synthesis of new comb-structure surfactants: One category: Terpolymer dispersants of carboxylate, sulfonate monomers and hydrophobic monomers, which are used in pesticide WDG formulations and can resist triple hard water; Two category: Terpolymer dispersants of carboxylate salts, non-ionic and hydrophobic monomers are used in pesticide water suspending agents. Non-ionic functional groups promote the stability of SC. Carboxylate forms a buffer system to improve the stability of pesticides in water; Three category: As a binary copolymer dispersant of vinylpyrazole and acrylic compounds, nitrogen heterocyclic molecules can destroy the hydration of pesticides, reduce the Aussie curing phenomenon of water suspending agents, and improve the fluidity of SC. Category four: copolymer of rosin vinyl ester and methacrylic acid, which can be used as a dispersant for viscosifying water-soluble granules, improving the use effect of pesticides. (4) Innovative process: 1) Select several rare earth element complex chain transfer agents, the amount is 100 times lower than that of conventional chain transfer agents, and the temperature is reduced by 20 degrees;2) Improve the polymer drying process, and the whole production process is free. Exhaust gas and wastewater discharge saves energy consumption of more than 3000 yuan per ton. Third-party evaluation: The product quality was evaluated on product use methods and quality at the Formulation Center of Anhui Research Institute of Chemical Industry, Safety Evaluation Center of Zhejiang Research Institute of Chemical Industry, Jiangsu Pesticide Institute, Hunan Research Institute of Chemical Industry, China Academy of Agricultural Sciences, and China Agricultural University. The product quality of the new preparations has reached industry standards. The application effect of some new additives exceeds that of foreign products and can replace advanced varieties such as 2700, T36, 1004, and 4894 produced abroad. The product has been tested in the acute oral toxicity test in rats, and the LD50 is greater than 5000mg/kg; it is a green and environmentally friendly product. The project obtained 1 software copyright, 4 authorized patents, 13 patent applications, published 14 scientific and technological papers, twice received national 863 project support, twice received national science and technology support support, and the project support of the Shanghai City Science and Technology Commission and Education Commission. Patented technology and proprietary innovative technology were promoted and applied in 8 domestic companies. In the past three years, the new output value has been 341 million yuan (including 163.29 million yuan for created additives and 177.712 million yuan for created dosage forms), 111.5 million yuan in new profits, and 31.19 million yuan in new taxes. Reduce the use of tens of thousands of tons of aromatic solvents in farmland. The research results were highly praised by Academician Li Zhengming and Academician Qian Xuhong.