The applicant is engaged in theoretical physical chemistry research and has focused on the exploration of basic chemical structures and its cutting-edge applications for many years. He started working full-time at Shanghai University (SHU) in September 2014. This application focuses on introducing the scientific research results completed by the applicant in China. Before joining Shanghai University, the applicant had published 195 papers with an h factor of 45; and obtained 26 scientific research projects (some of which were jointly applied by the team), with an average annual funding of 2.35 million yuan for 28 consecutive years. In view of the breakthrough results of ldquo; the role of the protein environment in the separation of primary charges in photosynthetic bacteria, the applicant won the Royal Australia Chemical Society's highest award in 2009. G. Smith Medal; elected Fellow of the Australia Academy of Sciences (FAA) in 2010. The applicant's research starts from a broad perspective, focuses on the most basic chemical principles, and applies them to solve the problems of the century and today's hot issues. Since joining Shanghai University full-time in September 2014, as of December 2016, applicants have published a total of 17 papers. The first unit of the eight representative papers selected in this application is Shanghai University. The research focuses on quantum mechanics, closely follows basic chemical ideas and their applications, and obtains the following important research results. (1) Quantum effects in electron-electron interactions that produce Van der Waals forces;(2) Applications of quantum theory in the field of protein structure, expanding new applications in molecular biology with new and efficient methods, such as X-ray crystallography and Cryo-EM Data analysis;(3) Innovatively integrating the above applications into computing software to reveal different types of 2D monolayer polymorphism control factors and induce chirality; this is the first time in academic circles;(4) Van der Waals forces transcend covalent and ionic forces to control the chemical synthesis of gold nanoparticles stabilized by sulfur monolayers; This study overturns the previous misunderstanding that the international academic community has had in this field for more than 30 years;(5) Describe the quantum coupling effect between electrons and nuclear movements, explaining the reaction mechanism of general chemical reactions; this new chemical perspective can be used to explain many issues, such as the huge differences in the chemical properties of the elements in the first row and the elements in the second row of the periodic table of chemical elements; Reveal non-adiabatic reactions and their quantum entanglement;(6) Reveal how charge separation occurs in all types of natural photosynthesis, draw important conclusions, end decades of debate in the international academic community, reach a general consensus in the academic community, and formulate a new framework for future research in the field of photosynthesis. Since 2016, the applicant has published a total of 23 papers with Shanghai University as the first unit. The research described above has been further expanded, and important discoveries have been published in the top international journals "Nature Reviews Chemistry","Nature Chemistry","PNAS" and "Chemical Science". "Nature Reviews Chemistry" studies gold-sulfur chemistry and successfully demonstrates that Van der Waals forces can be stronger than covalent bonds and ionic bonds in many chemical fields;"Chemical Science" further demonstrates the control and effects of ferroelectricity in two-dimensional materials. "PNAS" explains how to limit the van der Waals force in the Faraday cage and turn it off. This overturned a century-old misunderstanding of Van der Waals 'forces. "Nature Chemistry" proposed the final basic form of stereoisomers. This discovery, like the cis-trans isomers discovered in 1890 and the enantiomers discovered in 1848, is an epoch-making and important discovery in the field of chemistry.