Various VOCs generated during fuel combustion and production processes in the enterprise's factory area are removed and treated through the joint technology of "washing absorption & wet catalytic oxidation & adsorption and desorption". First, the water-soluble VOCs and fine particulate matter in the front-end tail gas are removed through the washing and absorption process. Wash water is circulated through a wet catalytic oxidation process to non-selectively oxidize organic matters in the water to CO2, H2O or mineral salts. The washed gas enters the adsorption system to complete the purification process. The new adsorbent developed in this system belongs to solid acid adsorbent, which has excellent adsorption and desorption properties for small molecule hydrocarbons, and is characterized by high stability and long service life. The dust concentration of tail gas emission is ≤20mg/m3; the concentration of non-methane total hydrocarbons emitted by tail gas is ≤50mg/m3. Taking a set of equipment with a control air volume of 33000 Nm3/h and an organic waste gas concentration of 1000 mg/m3 as an example, the power required for this technology is 100kw. Compared with RTO technology, it does not require additional natural gas fuel, which is efficient and energy-saving; Coupled with advanced oxidation method, fresh water is replaced every 10 days, a total of 9 tons of fresh water is reduced per day; 289080kg of volatile organic compounds are reduced every year.